
Estrogen & Progesterone
Our foundational menopause protocol — estrogen and progesterone together, dosed to your symptoms. The most complete way to start.
Provider-supervised hormone therapy for perimenopause and menopause. Estradiol and progesterone — sold together as a bundle or individually — to address hot flashes, sleep, mood, and more. Prescribed only when medically appropriate.

Treatment requires provider review. Your lab panel is included with your program. Not everyone qualifies.
Hormone therapy is prescribed only when clinically appropriate, following evaluation and lab review by a licensed provider. Not all patients qualify.
The Longevity Score is an educational estimate, not a diagnostic tool.
Perimenopause and menopause can affect almost everything. Your plan is built around the symptoms that matter most to you.
Start with the HRT bundle or a single hormone. Final treatment depends on your symptoms, history, and provider review.
Best for: the most complete way to start — estrogen and progesterone together, dosed to your symptoms.

Our foundational menopause protocol — estrogen and progesterone together, dosed to your symptoms. The most complete way to start.

Bioidentical estradiol for hot flashes, night sweats, sleep, and dryness — available as a cream or tablet.

Bioidentical progesterone to balance estrogen, protect the uterine lining, and support sleep when taken at night.
Compounded medications are not FDA-approved and require provider review. Estradiol and progesterone are prescribed only when clinically appropriate.
Research supports hormone therapy for menopausal symptoms in appropriately selected women, but benefits and risks vary by individual, timing, and route.
Perimenopause is the transition before menopause — often in your 40s — when hormones fluctuate and symptoms begin. Menopause is 12 months without a period. Hormone therapy can help in both stages.
"Bioidentical" means the estradiol and progesterone are identical to what your body makes. For healthy women starting near menopause, benefits often outweigh risks. Older WHI concerns were tied to a specific regimen in much older women. Your provider reviews your history to choose the safest approach.
Most women with a uterus and broad symptoms start with the HRT Bundle (estradiol + progesterone). If you've had a hysterectomy, estradiol alone may fit. If your concern is mainly sleep or skin/hair, a single therapy may be the right start.
Often therapy is started based on symptoms. Your provider may order labs (estradiol, FSH, thyroid, metabolic markers) to personalize your plan. Your lab panel is included with your HRT program — no separate lab fee.
Yes. You'll get order-status updates and shipment tracking by email at every step — when your prescription is reviewed, when the pharmacy fills it, and when it ships — so you always know where your order is. Everything is also visible in your account.
Everything you need is included. Your medication ships with all required supplies — nothing extra to buy, and no per-order shipping fee. Free shipping is included on every order.
Many women notice fewer hot flashes and night sweats within 2–6 weeks; sleep and mood often improve in a similar window.
Common, usually temporary effects include breast tenderness, bloating, and spotting. Hormone therapy is generally avoided with active hormone-sensitive cancer, unexplained vaginal bleeding, or a history of clots or stroke. Transdermal estradiol lowers clot risk vs. oral. A provider determines whether it's right for you.
Treatment options require provider review and may not be appropriate for everyone. Compounded medications are not FDA-approved. Hormone therapy requires individualized risk assessment and ongoing monitoring. Therapy is prescribed only for appropriate clinical indications, not for use without medical need.
Hormone changes are treatable, not inevitable. Start your visit in about five minutes.
Get Started →Perimenopause and menopause can affect almost everything. Here are the symptoms our providers most often treat — your plan is built around the ones that matter most to you.
Vasomotor symptoms are the hallmark of menopause — estradiol is the most effective treatment available.
Trouble falling or staying asleep, often tied to night sweats and falling progesterone.
Anxiety, low mood, and emotional swings linked to fluctuating hormones.
Difficulty concentrating and word-finding that many women notice in perimenopause.
Genitourinary symptoms that estrogen therapy can meaningfully improve.
Reduced desire that can have hormonal contributors worth evaluating.
Hormonal acne, oily skin, and unwanted hair that can accompany changing hormones.
Changing, unpredictable periods during the perimenopause transition.
Not every symptom has a hormonal cause, and hormone therapy isn't right for everyone. A licensed provider reviews your history and labs to determine whether treatment is appropriate.
Our foundational menopause & perimenopause protocol — estradiol and progesterone together, dosed to you. The most complete, best-value way to start.
Estradiol restores the estrogen your body is making less of, while progesterone balances it and protects the uterine lining. Together they address the broadest range of menopausal symptoms — hot flashes, night sweats, sleep, mood, and vaginal dryness.
Bioidentical estradiol to address hot flashes, night sweats, sleep disruption, and vaginal dryness — available as a cream or tablet.
Estradiol is the primary estrogen your ovaries produce less of during perimenopause and menopause. Replacing it is the most effective treatment for vasomotor symptoms (hot flashes and night sweats) and supports sleep, mood, and genitourinary health.
Bioidentical progesterone to balance estrogen, protect the uterine lining, and support sleep and calm.
Progesterone balances estrogen and is essential for protecting the uterine lining in women with a uterus who take estrogen. Many women also find it supports sleep and a sense of calm when taken in the evening.
Hormone therapy is a clinical treatment, not a lifestyle product. Eligibility is based on your symptoms, stage of life, and medical history, with labs to guide the plan. Most women in perimenopause or menopause with bothersome symptoms qualify, but a provider review is required.
Not all patients qualify for hormone therapy. Treatment requires evaluation by a licensed provider and ongoing lab monitoring.
You're likely a candidate if:
No clinic visits. No insurance hassles. Three steps, fully provider-supervised.
Complete a 5-minute health questionnaire about your symptoms, history, and goals. Upload recent labs if you have them.
A licensed provider reviews your intake, conducts an async consult or video visit, and decides if labs are necessary — included with your program, drawn at any Quest Diagnostics location. You'll never pay for a denied prescription.
Medication ships from a licensed 503A pharmacy. Quarterly provider reviews of your labs, dose adjustments, and provider check-ins, and your lab panel are included for as long as you stay on therapy.
Hot flashes, sleep loss, and brain fog have a physiology — and a solution. Your free assessment maps your symptoms and biological age in minutes, then shows whether hormone therapy fits your body.
Hormone therapy is well-established but not right for everyone. Here's what the research actually says about the most common concerns — directly, without softening.
Evidence suggests hormone therapy started within ~10 years of menopause or before age 60 has a more favorable cardiovascular profile than therapy started much later. Transdermal estradiol (cream/patch) is generally preferred over oral for women with clot or cardiovascular risk. Your provider weighs your individual timing and risk factors.
The WHI study raised concerns, but later analysis showed the risk is small, tied largely to the specific progestin and duration used, and does not apply equally to all regimens. Estrogen-alone (in women without a uterus) was not associated with increased breast cancer risk in WHI. Active or prior hormone-sensitive breast cancer is a disqualifying condition; routine screening continues during therapy.
Estrogen therapy is the most effective treatment available for hot flashes and night sweats, and it also helps preserve bone density, reducing the risk of osteoporosis and fractures after menopause. For many women these quality-of-life and long-term benefits are the central reason to consider therapy.
Oral estrogen carries a small increased risk of blood clots. Transdermal estradiol (cream or patch) has a lower clot risk and is often preferred, especially for women with clot history, migraine with aura, or higher BMI. Your provider selects the route and dose with your risk profile in mind.
Most women start with the HRT Bundle (estradiol + progesterone together). Your licensed provider will recommend the right approach based on your symptoms and labs.
Your HRT program already includes the labs your provider needs to personalize and monitor your plan — estradiol, FSH, thyroid (TSH), and a metabolic panel. Want a clearer picture of your health? Add the Comprehensive Women's Health Panel for a deeper read, with cardiac and longevity markers included.
Hormonal decline is gradual — but it compounds. Catching it early and treating it appropriately preserves muscle, mood, drive, and metabolic health into your 50s, 60s, and beyond. Start with a free longevity assessment, or check eligibility with a licensed provider.